Pentobarbital causes drowsiness. However, the consumption of basil essential oil is not advised in case of:

Bergamot (Citrus bergamia) Phototoxic – avoid … – Dermatitis or redness of the skin: the essential oil can be irritating and should not be … Surgery: Basil oils and extracts might slow blood clotting. Avoid during pregnancy. Basil essential oil should be avoided during pregnancy since it can have an impact on hormonal levels as well as muscle and nerve function.

– Lactation: it is not known if basil is safe during breast-feeding. Avoid the following essential oils: aniseed, basil, camphor, cinnamon bark, clove bud, clove leaf, eucalyptus radiata fennel, hyssop, juniper, lemongrass, marjoram, nutmeg, oregano, parsley seed, peppermint (under 12), pennyroyal, sage, savory, tagetes and thyme. The flavors and scents of basil are so diverse that you can come across tastes and scents like citrus, licorice, cinnamon, and more. Essential Oil: Contraindications: Basil (Ocimum basilicum) May irritate sensitive skin.

In theory, basil oils or extracts might increase the risk of bleeding during surgical procedures.

The medicinal parts of the basil plant are the leaves and the seeds. Best not used on children under 4 years old. Interactions and Side Effects of Basil Essential Oil. Benzoin (Styrax benzoin) May cause some skin sensitivity. Basil essential oil will retain the aroma of the herb, depending on the type that was used in the process of essential oil extraction.. Basil is a safe herb, on which no contraindications have been described, except in those situations in which the person is sensitive or allergic to its composition. Basil toxicity – The essential oil can cause dermatitis used in external application. Pentobarbital interacts with HOLY BASIL. The estragole can cause uterine contractions, so that basil is contraindicated during pregnancy.

It’s also not appropriate for anyone with epilepsy.

There is some concern that taking holy basil seed oil with pentobarbital might cause too much drowsiness.
– In internal use it may irritate the digestive mucosa and is not recommended in cases of gastritis. – At high doses it is considered narcotic.